Episode 97: 2023 Resuscitation Update

The gang gets back together and discusses new resuscitation data from 2022.

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest

Question and Methods: double-blind RCT out of Denmark whether high or low arterial blood-pressure targets would be superior in preventing death or severe anoxic brain injury in comatose survivors of OHCA. Enrolled 789 patients

RePHILL Study

Question and Methods: Multicenter RCT out of the UK that investigated prehospital resuscitation using PRBCs and plasma versus normal saline to improve tissue perfusion or mortality in adult trauma patients with hemorrhagic shock.

Mike's favorite study about Refractory VFib

Question and Methods: Shock-refractory VFib remains a common occurrence during OHCA → does dual sequential defib and vector-changing defib improve outcomes in patients with refractory VF? Primary outcome measure was survival to hospital discharge; secondary outcomes termination of VF, ROSC, good neurologic outcome at hospital discharge

Head and thorax elevation during cardiopulmonary resuscitation using circulatory adjuncts is associated with improved survival

Question and Methods: Does the use of a head up device as part of a CPR bundle improve survival from OHCA?